51 static const d1 = 1.8e-11;
61 static const d2 = 1.86e-11;
70 static const d3 = 1.89e-11;
79 static const d4 = 2.27e-11;
88 static const d5 = 1.8720e-11;
97 static const d6 = 1.9548e-11;
106 static const d7 = 1.4850e-11;
115 static const d8 = 1.4850e-11;
124 static const K1 = 0.08;
133 static const K2 = 0.08;
142 static const K3 = 0.054;
151 static const K4 = 0.36;
160 static const K5 = .0005;
169 static const K6 = .0005;
178 static const K7 = 3.6000e-4;
187 static const K8 = 1.8000e-04;
196 static const K9 = .0005;
223 static const K12 = 1.8000e-05;
232 static const K13 = 1.8000e-4;
241 static const Km3 = 0.0360;
286 static const Km12 = 1.8000e-06;
295 static const tc = 1e-7;
305 static const L = 1e-5;
349 this.
tau= this.
L^2/this.
d1;
351 s = sampling.GridSampler;
356 o = solvers.MLode15i;
365 s = models.pcdi.PCDISystem3D(
this);
366 this.
Name=
" Programmed Cell Death 3D ";
369 s = models.pcdi.PCDISystem2D(
this);
370 this.
Name=
" Programmed Cell Death 2D ";
373 if this.WithInhibitors
374 this.
Name= [this.Name
" (Inhibitor System) "];
377 s.MaxTimestep= this.
dt;
381 sr = spacereduction.PODGreedy;
398 this.
System.plot(
this, varargin[:]);
409 this.
System.plotState(
this, varargin[:]);
420 #if 0 //mtoc++: 'get.Dimension'
429 #if 0 //mtoc++: 'set.WithInhibitors'
431 if ~islogical(value) || ~isscalar(value)
447 m = models.pcdi.PCDIModel;
static function res = test_PCDIModel_Simulation()
static const d5
Typical diffusion rate for IAP [m^2/s].
char Name
The name of the Model.
static const d7
Typical diffusion rate for YAI [m^2/s].
static const K13
XAP degradation rate.
static const d6
Typical diffusion rate for BAR [m^2/s].
static const K1
Procaspase-8 to Caspase-8 reaction rate.
static const d1
% System Coefficient values Typical diffusion rate for Caspase-8 [m^2/s]
PCDIModel(integer dim,logical inhibitors)
Creates a new instance of the PCDModel.
function useFileTrajectoryData(logical overwrite)
Sets the TrajectoryData and TrajectoryFxiData classes to filesystem based versions.
static const Km10
Procaspase-3 production rate.
The base class for any KerMor detailed model.
double dt
The desired time-stepsize for simulations.
sampling.BaseSampler Sampler
The sampling strategy the Model uses.
models.BaseFirstOrderSystem System
The actual dynamical system used in the model.
static const K3
IAP-Caspase 3 (de)reaction rate.
static const d3
Typical diffusion rate for Pro-Caspase-8 [m^2/s].
static const d4
Typical diffusion rate for Pro-Caspase-3 [m^2/s].
static const Km8
IAP production rate.
static const Km12
BAR production rate.
static const K8
IAP degradation rate.
static const L
Typical cell length (from 1D) [m].
static const K2
Procaspase-3 to Caspase-3 reaction rate.
WithInhibitors
Flag that detemines if this model uses inhibitors.
A variable number of input arguments.
static const K5
Caspase-8 degradation rate.
function ss = getSteadyStates(n)
double tau
Time scaling factor .
solvers.BaseSolver ODESolver
The solver to use for the ODE. Must be an instance of any solvers.BaseSolver subclass.
static const K4
IAP-Caspase 3 one-way (de)reaction rate.
Base class inhibitor PCD models.
static const K12
BAR degradation rate.
function plot(varargin)
Overrides standard method and forwards to the system's plot function. (they are 1D and 2D) ...
approx.BaseApprox Approx
The approximation method for the CoreFunction.
static const K10
Caspase-3 degradation rate.
double T
The final timestep up to which to simulate.
data.ModelData Data
The full model's data container. Defaults to an empty container.
spacereduction.BaseSpaceReducer SpaceReducer
The reduction algorithm for subspaces.
static const K11
BAR - Procaspase-8 (de)reaction rate.
static const K6
Caspase-3 degradation rate.
function plotState(varargin)
Overrides standard method and forwards to the system's plot function. (they are 1D and 2D) ...
static const d2
Typical diffusion rate for Caspase-3 [m^2/s].
static const tc
% System Rescaling settings Typical concentration [Mol]
static const Km3
YAI to IAP production rate.
static const K9
Pro-Caspase-8 degradation rate.
static const K7
YAI degradation rate.
static const Km9
Procaspase-8 production rate.
static const Km11
XAB degradation rate.
static const d8
Typical diffusion rate for XAB [m^2/s].